Our research bridges computational and experimental sciences to discover new regulatory aspects in the human genome - - Specifically how long noncodng RNA (lncRNA) genes regulate numerous biological processes.
Our teaching aims to enable all students to perform bioinformatic and data science analyses on ever emerging forms of genome-wide data such as RNA-seq, ChIP-seq, ATAC-seq ......
"Now teaching at the University of Colorado in Boulder, John Rinn focuses on research into the influence of ribonucleic acid (RNA) on establishing unique cellular states in development and disease. His research focus on the noncoding positions of the human genome, the regions that don’t encode for classic protein coding genes. This requires modifying the human genome in stem cell lines to uncover novel regulatory elements that are required to maintain the pluripotent state or prevent cellular differentiation. This also requires genome modifications that represent those identified in human disease, the vast majority of which reside in the noncoding genome..." Read the entire article here. John Rinn lab website
"Former Harvard University professor John Rinn is a Leslie Orgel professor of RNA science at the University of Colorado (UC), Boulder. More specifically, John Rinn is a faculty member of the Interdisciplinary Quantitative (IQ) Biology PhD program offered through the institution’s BioFrontiers Institute..." John Rinn lab website
Discovery of HOTAIR, ROR, FIRRE and other lncRNAs "A former professor of stem cell and regenerative biology at Harvard University, John Rinn recently became the Marvin H. Caruthers Endowed Chair for Early-Career Faculty at the BioFrontiers Institute at the University of Colorado Boulder, where he is also the Leslie Orgel Professor of RNA Science. While studying for his PhD in molecular biophysics and biochemistry at Yale University, John Rinn discovered that the human genome encoded numerous new RNA genes call long noncoding RNAs or large intervening non-coding RNAs (lincRNA)...or more commonly lncRNA" Article in Harvard Gazzette